Malignant transformation in a solitary dermal cylindroma

We describe a case of a solitary dermal cylindroma with focal malignant transformation. The scalp tumor measured 3 cm in greatest dimension and was successfully surgically excised. The patient has been followed up for the last two years with no recurrences. Changes of malignant transformation includ...

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Bibliographic Details
Published inArchives of pathology & laboratory medicine (1976) Vol. 111; no. 8; pp. 765 - 767
Main Authors Lin, P Y, Fatteh, S M, Lloyd, K M
Format Journal Article
LanguageEnglish
Published United States 01.08.1987
Subjects
Aged
Carcinoma, Adenoid Cystic - pathology
Humans
Male
Scalp - pathology
Skin Neoplasms - pathology
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Summary:We describe a case of a solitary dermal cylindroma with focal malignant transformation. The scalp tumor measured 3 cm in greatest dimension and was successfully surgically excised. The patient has been followed up for the last two years with no recurrences. Changes of malignant transformation included loss of peripheral palisading, destruction of the hyaline sheath, areas of necrosis, and pleomorphism of nuclei with frequent mitosis. We reviewed data on 12 other reported cases of dermal cylindromas with malignant transformation. Morphologic features of both benign cylindromas and their malignant counterparts are described. The literature was reviewed regarding the controversy of the cell of origin.
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ISSN:0003-9985