Striated muscle ultrastructure in intermittent claudication

Twenty-four biopsy specimens from the lower leg muscles of 21 patients with intermittent claudication were studied by electron microscopy. Sixteen of the specimens contained hypertrophic, atrophic, autolytic, or phagocytic fibers, or other forms of macroscopic fiber degeneration. Of the pathological...

Full description

Saved in:
Bibliographic Details
Published inArchives of pathology & laboratory medicine (1976) Vol. 101; no. 5; pp. 230 - 235
Main Authors Teräväinen, H, Mäkitie, J
Format Journal Article
LanguageEnglish
Published United States 01.05.1977
Subjects
Aged
Basement Membrane - ultrastructure
Biopsy
Female
Glycogen - metabolism
Histocytochemistry
Humans
Intermittent Claudication - metabolism
Intermittent Claudication - pathology
Male
Middle Aged
Muscles - metabolism
Muscles - pathology
Muscles - ultrastructure
Myofibrils - ultrastructure
Phagocytosis
Vacuoles - ultrastructure
Online AccessGet full text

Cover

More Information
Summary:Twenty-four biopsy specimens from the lower leg muscles of 21 patients with intermittent claudication were studied by electron microscopy. Sixteen of the specimens contained hypertrophic, atrophic, autolytic, or phagocytic fibers, or other forms of macroscopic fiber degeneration. Of the pathological changes in the cell organelles, the most common was simple myofibrillar degeneration, followed by slightly pathological mitochondria and excessive accumulations of glycogen and lipofuscin. Different types of basement membrane alterations and central nuclei were present in 16 of the biopsy specimens. Most of the pathological changes were the same as those previously reported by others to occur in specific diseases of muscle. There was some positive correlation of the degree of pathological changes to the estimated clinical severity of claudication.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0003-9985