Contraction of cat nictitating membrane by tetramisole

Tetramisole produced a dose-dependent persistent contraction of cat nictitating membrane. This was not significantly altered by prior adrenalectomy or reserpinisation and tyraminisation, but was abolished by prior alpha blockade.

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Bibliographic Details
Published inArchives internationales de pharmacodynamie et de thérapie Vol. 238; no. 1; p. 14
Main Authors Dhume, V G, Pereira, J S, Diniz, R S, Abraham, G J
Format Journal Article
LanguageEnglish
Published Belgium 01.03.1979
Subjects
Adrenalectomy
Animals
Cats
Female
In Vitro Techniques
Male
Muscle Contraction - drug effects
Muscle, Smooth - drug effects
Nictitating Membrane - drug effects
Phenoxybenzamine - pharmacology
Reserpine - pharmacology
Tetramisole - pharmacology
Tyramine - pharmacology
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Summary:Tetramisole produced a dose-dependent persistent contraction of cat nictitating membrane. This was not significantly altered by prior adrenalectomy or reserpinisation and tyraminisation, but was abolished by prior alpha blockade.
ISSN:0003-9780