Biological studies on the effects of some therapeutic procedures used in psychiatry

The glucose, lactate, and pyruvate levels, the lactate/pyruvate ratio and pH were studied in serum and CSF of patients with schizophrenia, reactive psychosis, symptomatic or circular psychosis under the effect of atropine coma, ES and pentetrazole convulsions, tranquilizer treatment and combined the...

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Bibliographic Details
Published inActa physiologica Academiae Scientiarum Hungaricae Vol. 46; no. 1; p. 59
Main Author Zsadányi, O
Format Journal Article
LanguageEnglish
Published Hungary 1975
Subjects
Atropine - pharmacology
Atropine - therapeutic use
Blood Glucose - metabolism
Electroencephalography
Electroshock
Glucose - cerebrospinal fluid
Humans
Hydrogen-Ion Concentration
Lactates - blood
Lactates - cerebrospinal fluid
Lactates - metabolism
Pentylenetetrazole - pharmacology
Pentylenetetrazole - therapeutic use
Psychotic Disorders - therapy
Pyruvates - blood
Pyruvates - cerebrospinal fluid
Pyruvates - metabolism
Tranquilizing Agents - pharmacology
Tranquilizing Agents - therapeutic use
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Summary:The glucose, lactate, and pyruvate levels, the lactate/pyruvate ratio and pH were studied in serum and CSF of patients with schizophrenia, reactive psychosis, symptomatic or circular psychosis under the effect of atropine coma, ES and pentetrazole convulsions, tranquilizer treatment and combined therapy. Convulsive therapy caused a disorder in cerebral carbohydrate metabolism while no similar changes were induced by atropine coma. Anaerobic carbohydrate metabolism was stimulated by combined therapy. This treatment had the best effect and the changes caused by it were slighter than in the case of convulsive therapy. The changes in EEG frequency corresponded to the biochemical changes.
ISSN:0001-6756