Drug Transporters and Their Role in Absorption and Disposition of Peptides and Peptide-Based Pharmaceuticals

This chapter contains sections titled: Introduction Transport systems mediating peptide‐based pharmaceutical absorption and disposition Gastrointestinal‐tract‐specific transporter activity In vitro/In vivo case studies: utilizing transport systems for drug delivery Conclusions Acknowledgments Refere...

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Published inOral Bioavailability Vol. 16; pp. 291 - 308
Main Author Li, Xiaoling
Format Book Chapter
LanguageEnglish
Published United States Wiley 2011
John Wiley & Sons, Inc
Subjects
CHEMISTRY
drug transporters, absorption ‐ peptides and peptide‐based pharmaceuticals, predicting ADMET
identifying molecular requirements of compounds ‐ targeting drugs, formulation design
transport systems, peptide‐based absorption ‐ solute carrier (SLC) family, ATP‐Binding Cassette (ABC) transporters
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Summary:This chapter contains sections titled: Introduction Transport systems mediating peptide‐based pharmaceutical absorption and disposition Gastrointestinal‐tract‐specific transporter activity In vitro/In vivo case studies: utilizing transport systems for drug delivery Conclusions Acknowledgments References
ISBN:0470260998
9780470260999
DOI:10.1002/9781118067598.ch18