Treatment efficacy of Lianhua Qingwen capsules for eraly-stage COVID-19

• Published in: American journal of translational research Vol. 14; no. 2; pp. 1332 - 1338
• Main Authors: Fan, Si-Jia, Liao, Jian-Kun, Wei, Liu, Wang, Bai-Yu, Kai, Liu, Tan, Du-Xun
• Format: Journal Article
• Language: English
• Published: United States e-Century Publishing Corporation 01.01.2022
• Subjects: Original; COVID-19; total effective rate; traditional Chinese medicine (TCM) treatment; clinical symptoms; Lianhua Qingwen; retrospective study
• ISSN: 1943-8141; 1943-8141

To systematically determine the effect of Lianhua Qingwen Capsules on the early antiviral and anti-inflammatory action against COVID-19 (Coronavirus 2019) and its applicational value in the treatment of COVID-19. The clinical data of 66 early-mid-stage COVID-19 patients admitted to hospitals in Guangzhou between January 2020 and April 2020 were retrospectively analyzed. The patients receiving Lianhua Qingwen Capsule treatment were assigned to the observation group (n=33) and those given conventional therapy were included in the control group (n=33). The two groups were compared in terms of clinical effects and main symptom (fever, cough and fatigue) disappearance rate. In comparison with the control group, 1) the total effective rate was significantly higher in the observation group (P<0.05); 2) the disappearance rates of fever, cough and fatigue were statistically higher in the observation group; 3) the treatment time was significantly shorter and patient recovery was significantly better in the observation group; 4) the laboratory index levels [white blood cell (WBC), interleukin-6 (IL-6), serum amyloid A (SAA)] were better in the observation group. Lianhua Qingwen Capsules can significantly improve the total effective rate for COVID-19 patients, as well as shorten the hospital stay and treatment time, which is worth of promotion in the clinic.