A mathematic analysis of different manners of replacement fluid infusion in continuous veno-venous hemofiltration

• Published in: Zhonghua wei zhong bing ji jiu yi xue Vol. 27; no. 5; p. 332
• Main Authors: Wu, Yunzhen, Wang, Chunting
• Format: Journal Article
• Language: Chinese
• Published: China 01.05.2015
• Subjects: Blood Coagulation; Hemofiltration; Humans; Mathematics; Renal Replacement Therapy
• ISSN: 2095-4352
• DOI: 10.3760/cma.j.issn.2095-4352.2015.05.003

To establish a mathematical formula for choosing the manner of replacement fluid infusion in continuous renal replacement therapy (CRRT), so as to provide the basis for improving the treatment effect. A mathematical formula for choosing the manner of replacement fluid infusion with continuous veno-venous hemofiltration (CVVH) was taken as an example, and it was compared with the result of standard replacement fluid in order to analyze the effect of different manners of infusion. (1) Comparison parameters: the plasma volume ("Vreturn") and some electrolyte concentration ("Creturn") in back way of CRRT ( if other thing was solute, filter coefficient should be 1.0). (2) Research objects: the actual replacement fluid (for example, the most complex should be sorted into A and B type) mode (pre or post) was compared with the standard replacement fluid (the A and B in one). (3) Based on the formula of standard replacement, four equations in different conditions were derived: pre-dilution and post-dilution mode; same