Effect of propofol upon brain after whole-body hyperthermia in rats

• Published in: Zhong hua yi xue za zhi Vol. 89; no. 33; p. 2356
• Main Authors: Zhao, Xin, Jin, Yan-Wu, Wang, Duan-Yu, Wang, Zhi-Gang
• Format: Journal Article
• Language: Chinese
• Published: China 08.09.2009
• Subjects: Animals; Apoptosis - drug effects; Brain - drug effects; Brain - pathology; Disease Models, Animal; Heat Stress Disorders; Hippocampus - cytology; Male; Neurons - ultrastructure; Propofol - pharmacology; Rats; Rats, Wistar

To investigate the effect of propofol upon acute cerebral insult during whole-body hyperthermia (WBH) in rats. Sixty male Wistar rats were randomly divided into 6 groups. All the animals were trained with place navigation test of Morris water maze (MWM) for 5 days pre-study. After training, some rat...