Abdominal inflammatory myofibroblastic tumor: report on four cases and review of literature

The Abdominal Inflammatory Myofibroblastic Tumor (AIMT) is a rare tumor with unknown etiology which usually occurs in children and adolescents. It is composed of myofibroblastic spindle cells intermixed with inflammatory cells. We present four cases of AIMT. WE HEREIN PRESENT FOUR CASES OF AIMT IN D...

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Published inMajallah-ʼi bīmārīhā-yi kūdakān-i Īrān = Iranian journal of pediatrics Vol. 21; no. 4; pp. 543 - 548
Main Authors Mirshemirani, Alireza, Tabari, Ahmad Khaleghnejad, Sadeghian, Naser, Shariat-Torbaghan, Siamak, Pourafkari, Marina, Mohajerzadeh, Leila
Format Journal Article
LanguageEnglish
Published Iran Tehran University of Medical Sciences 01.12.2011
Subjects
Case Report
Stomach
Duodenum
Malignancy
Colon
Mesenteric
Abdomen
Inflammatory myofibroblastic tumor
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Summary:The Abdominal Inflammatory Myofibroblastic Tumor (AIMT) is a rare tumor with unknown etiology which usually occurs in children and adolescents. It is composed of myofibroblastic spindle cells intermixed with inflammatory cells. We present four cases of AIMT. WE HEREIN PRESENT FOUR CASES OF AIMT IN DIFFERENT AGES (RANGE: 3.5 to 13 years) and in different organs (stomach, periduodenal, mesenteric, and colon). There were two females and two males. The main symptoms were abdominal pain/mass/obstruction, vomiting, and weight loss. In all four patients, diagnosis was made by laparatomy and pathologic examination of excised mass lesion. Three patients underwent complete excision and no residual disease was present, one patient received chemotherapy due to tumor recurrences. The patients were followed up in average for four years. As the imaging and laboratory tests are non-specific, the diagnosis of AIMT is rarely made before surgery. AIMT should, therefore, be considered when a mass arises in an unusual location in the pediatric age group. Complete surgical resection should be performed whenever possible and the child should be kept on long-term follow-up.
ISSN:2008-2142
2008-2150