Spectrophotometric Method for Determination of Bambuterol Hydrochloride in Bulk and Tablets

A simple, rapid, precise and accurate spectrophotometric method has been developed for estimation of Bambuterol hydrochloride from tablet formulation. In methanol, Bambuterol showed absorbance in the visible range at 265 nm. Linearity was observed in the concentration range of 40-240 μgmL-1 (r2= 0.9...

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Bibliographic Details
Published inOriental journal of chemistry Vol. 24; no. 2; p. 769
Main Authors Pawar, Varun, Lalitha, N, Puranik, S B, Sanjay Pai, P N, Rao, G K
Format Journal Article
LanguageEnglish
Published Bhopal Oriental Scientific Publishing Company 01.01.2008
Subjects
Linearity
Recovery
Spectrophotometry
Tablets
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Summary:A simple, rapid, precise and accurate spectrophotometric method has been developed for estimation of Bambuterol hydrochloride from tablet formulation. In methanol, Bambuterol showed absorbance in the visible range at 265 nm. Linearity was observed in the concentration range of 40-240 μgmL-1 (r2= 0.9990). The assay results were found to be in good agreement with label claim. The recovery studies were carried out at three different levels i.e. at 80%, 100%, 120%. The method was validated statistically and by recovery studies.
ISSN:0970-020X
2231-5039