Synthesis of Gd2O3 nanoparticles for MRI contrast agents

Gd2O3 nanoparticles were synthesized by using our original method for application as MRI contrast agents. The sample diameters were controlled in the range 18–66 nm by adjusting the annealing temperature between 773 and 1273 K in air or in an Ar atmosphere. Magnetization measurements were performed...

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Bibliographic Details
Published inJournal of physics. Conference series Vol. 352; no. 1
Main Authors Sakai, N, Zhu, L, Kurokawa, A, Takeuchi, H, Yano, S, Yanoh, T, Wada, N, Taira, S, Hosokai, Y, Usui, A, Machida, Y, Saito, H, Ichiyanagi, Y
Format Journal Article
LanguageEnglish
Published Bristol IOP Publishing 01.01.2012
Subjects
Contrast agents
Diameters
Gadolinium oxides
Magnetic moments
Nanoparticles
Paramagnetism
Physics
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Summary:Gd2O3 nanoparticles were synthesized by using our original method for application as MRI contrast agents. The sample diameters were controlled in the range 18–66 nm by adjusting the annealing temperature between 773 and 1273 K in air or in an Ar atmosphere. Magnetization measurements were performed at 300 K, and the effective magnetic moment of each sample was calculated. They showed paramagnetism at 300 K and they had large effective magnetic moment μeff of 7.15–8.05 μB. MRI measurements were performed in 0.8 wt% agarose solution, and the Gd2O3 nanoparticles were found to work as effective T1-shortening MRI contrast agents.
ISSN:1742-6588
1742-6596
DOI:10.1088/1742-6596/352/1/012008