Application of Nanocomposite Coatings with Different Structural Physical and Chemical Characteristics in Tissue Engineering

The research covers the results of experimental studies of the effect character of nanocomposite coatings with different physical and chemical parameters (type, roughness, hydrophilic-hydrophobic characteristics) on structural and functional properties (adhesive potential, phenotype, gene expression...

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Published inJournal of Nano- and Electronic Physics Vol. 5; no. 1; p. 1008-1
Main Authors Goltsev, A N, Rassokha, I V, Dubrava, T G, Ostankova, L V, Ostankov, M V, Gordienko, E A, Safonov, V I, Zykova, A V
Format Journal Article
LanguageEnglish
Published Sumy Ukraine Sumy State University, Journal of Nano - and Electronic Physics 01.01.2013
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Summary:The research covers the results of experimental studies of the effect character of nanocomposite coatings with different physical and chemical parameters (type, roughness, hydrophilic-hydrophobic characteristics) on structural and functional properties (adhesive potential, phenotype, gene expression) of mesenchymal stem cells (MSCs). On the tested nanocoatings (Al2 O3 , ZrO2 , Ta2 O5 ) the capability of oxide coating Al2O3 to enrich the in vitro cultured bone marrow (BM) with the cells of MSCs phenotype markers as well as to increase the expression rate of ido gene in them, which may extend the spectrum of their therapeutic application in clinics, has been found.
ISSN:2077-6772
2306-4277