Molecular analysis of Hodgkin's disease with abundant Reed-Sternberg cells

• Published in: Hematologic pathology Vol. 4; no. 1; p. 27
• Main Authors: Hu, E H, Ellison, D, Zovich, D, Nichols, P, Pattengale, P
• Format: Journal Article
• Language: English
• Published: United States 1990
• Subjects: Cell Count - methods; Cloning, Molecular; Gene Rearrangement - immunology; Hodgkin Disease - genetics; Hodgkin Disease - immunology; Hodgkin Disease - pathology; Humans; Phenotype

The pathogenesis of Hodgkin's disease (HD) has been elusive largely because of the paucity of the Reed-Sternberg cells in comparison to large numbers of normal inflammatory cells in biopsy specimens. This report attempts to characterize Hodgkin's disease by studying subtypes with a high pr...