Pigmented onychomatricoma: A clinical simulator that could not mislead ultrasound

• Published in: Acta bio-medica : Atenei Parmensis Vol. 92; no. S1; p. e2021158
• Main Authors: Peruilh-Bagolini, Leonardo, Dossi, Maria Teresa, Wortsman, Ximena, Montero, Tabata
• Format: Journal Article
• Language: English
• Published: Italy Mattioli 1885 30.04.2021
• Subjects: Case Report
• ISSN: 0392-4203; 2531-6745
• DOI: 10.23750/abm.v92iS1.9519

Onychomatricoma is a rare subungual tumor composed of stroma and nail matrix-like epithelium. Only seven cases of the pigmented variant have been reported in the literature. We present a 62-year-old male patient with a 2-years history of a single fingernail thickening, deformation, and hyperpigmentation. He had been treated for onychomycosis, without improvement. Due to the increasing hyperpigmentation, and to rule out tumoral entities, including melanoma, a color Doppler ultrasound examination of the nail was requested, which showed a hypoechoic tumor of the nail matrix and bed, with hyperechogenic linear images inside, suggesting the diagnosis of onychomatricoma. Onychectomy and partial matricectomy were performed. Histological evaluation confirmed the diagnosis of onychomatricoma. Discusion and conclusion: Histological evaluation is the gold standard for the diagnosis of onychomatricoma. However, ultrasonography represents an easily accessible, non-invasive diagnostic tool for the initial evaluation of these tumors, especially in unsuspected atypical clinical presentations.