Vascular endothelial growth factor (VEGF) modulation by targeting hypoxia-inducible factor-1α → hypoxia response element → VEGF cascade differentially regulates vascular response and growth rate in tumors

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Bibliographic Details
Published inCancer research (Chicago, Ill.) Vol. 60; no. 22; pp. 6248 - 6252
Main Authors TSUZUKI, Yoshikazu, FUKUMURA, Dai, OOSTHUYSE, Bert, KOIKE, Chieko, CARMELIET, Peter, JAIN, Rakesh K
Format Journal Article
LanguageEnglish
Published Philadelphia, PA American Association for Cancer Research 15.11.2000
Subjects
Biological and medical sciences
Cell physiology
Fundamental and applied biological sciences. Psychology
Molecular and cellular biology
Signal transduction
Cell proliferation
Angiogenic factor
Rodentia
Malignant tumor
Response element
In vitro
Inductor
Angiogenesis
In vivo
Signal transduction
Vertebrata
Mammalia
Vascular endothelium growth factor
Mouse
Animal
Modulation
Established cell line
Hypoxia
Neovascularization
Mechanism of action
Tumor cell
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ISSN:0008-5472
1538-7445