Transient elevation in catalytic trkB mRNA during postnatal development of the rat brain

• Published in: Neuroreport Vol. 4; no. 9; p. 1091
• Main Authors: Dugich-Djordjevic, M M, Ohsawa, F, Hefti, F
• Format: Journal Article
• Language: English
• Published: England 01.09.1993
• Subjects: Animals; Brain - anatomy & histology; Brain - growth & development; Brain Chemistry - physiology; Female; Hippocampus - growth & development; Hippocampus - metabolism; In Situ Hybridization; Nerve Growth Factors - biosynthesis; Nerve Tissue Proteins - biosynthesis; Neurotrophin 3; Pregnancy; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases - biosynthesis; RNA Probes; RNA, Messenger - biosynthesis; Sulfur Radioisotopes; Thalamic Nuclei - growth & development; Thalamic Nuclei - metabolism

Quantitative in situ hybridization analysis of catalytic (trkB TK+) and non-catalytic (trkB TK-) trkB mRNAs in the postnatal rat brain demonstrated regional differences in expression and revealed transient increases in trkB TK+ expression. Hybridization of trkB TK+ mRNA was observed in thalamic nucl...