A Rare Presentation of Central Nervous System Tuberculomas in an Immunocompetent Patient

The uncommon presentation of simultaneous brain and lung lesions in an immunocompetent adult patient with frequent travel to a mycobacterium tuberculosis (MTB) endemic area requires high clinical suspicion for central nervous system (CNS) MTB, as this disease often results in severe neurologic morbi...

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Published inHawai'i journal of health & social welfare Vol. 81; no. 6; pp. 151 - 154
Main Authors Chang, Bryce K, Adlawan, Jacqueline, Fesenmeier, Samuel, Kaminskas, David, Carrazana, Enrique, Liow, Kore K
Format Journal Article
LanguageEnglish
Published United States University Clinical, Education & Research Associate (UCERA) 01.06.2022
Subjects
Adult
Central Nervous System
Humans
Mycobacterium tuberculosis - genetics
Tuberculoma
simultaneous brain and lung lesions
mycobacterium tuberculosis
central nervous system
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Summary:The uncommon presentation of simultaneous brain and lung lesions in an immunocompetent adult patient with frequent travel to a mycobacterium tuberculosis (MTB) endemic area requires high clinical suspicion for central nervous system (CNS) MTB, as this disease often results in severe neurologic morbidity and mortality. Non-specific and subacute symptoms make the diagnosis of CNS MTB clinically challenging, and a workup with imaging and microbiological studies such as acid-fast bacilli staining, nucleic acid amplification testing, and tissue culture must not delay prompt treatment with anti-tuberculosis therapy. This case illustrates the complex challenges of medical diagnosis and multi-disciplinary decision-making involved in the workup of CNS MTB.
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ISSN:2641-5216
2641-5224