In vitro effect of haemagglutination inhibition antibodies on measles virus replication

Children between the ages of 6 and 15 years were studied for the presence of serum levels of measles haemagglutination inhibition antibodies in relation to the continual measles epidemics in Nigeria. The neutralization of Edmonston B strain of live measles virus by such antibodies was also studied i...

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Bibliographic Details
Published inMicrobios Vol. 43; no. 174-175; p. 181
Main Authors Odama, L E, Eghafona, N O, Emejuaiwe, S O
Format Journal Article
LanguageEnglish
Published England 1985
Subjects
Adolescent
Animals
Antibodies, Viral - immunology
Cell Line
Cercopithecus aethiops
Child
Cytopathogenic Effect, Viral
Hemagglutination Inhibition Tests
Humans
Measles - immunology
Measles virus - immunology
Measles virus - physiology
Neutralization Tests
Nigeria
Virus Replication
Nigeria
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Summary:Children between the ages of 6 and 15 years were studied for the presence of serum levels of measles haemagglutination inhibition antibodies in relation to the continual measles epidemics in Nigeria. The neutralization of Edmonston B strain of live measles virus by such antibodies was also studied in Vero cells. The results indicate that in Vero cells, replication of the virus could be inhibited for up to 3 days by haemagglutination inhibition antibody at a concentration of 1:16.
ISSN:0026-2633