Comparative evaluation of antimicrobial efficacy of QMix™ 2 in 1, sodium hypochlorite, and chlorhexidine against Enterococcus faecalis and Candida albicans

The aim of this study is to compare the antimicrobial efficacy of QMix™ 2 in 1, sodium hypochlorite (NaOCl), and chlorhexidine (CHX) against Enterococcus faecalis and Candida albicans. Eighty freshly extracted, single-rooted human mandibular premolar teeth were instrumented and autoclaved. Samples w...

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Published inJournal of conservative dentistry Vol. 18; no. 2; pp. 128 - 131
Main Authors Elakanti, Soujanya, Cherukuri, Gayathri, Rao, Venkateswara G, Chandrasekhar, Veeramachaneni, Rao, Anitha S, Tummala, Muralidhar
Format Journal Article
LanguageEnglish
Published India Medknow Publications & Media Pvt Ltd 01.03.2015
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Summary:The aim of this study is to compare the antimicrobial efficacy of QMix™ 2 in 1, sodium hypochlorite (NaOCl), and chlorhexidine (CHX) against Enterococcus faecalis and Candida albicans. Eighty freshly extracted, single-rooted human mandibular premolar teeth were instrumented and autoclaved. Samples were divided into two groups of 40 teeth each based on the type of microorganism used. Group I was inoculated with E. faecalis and Group II with C. albicans and incubated for 3 days. Each group was subdivided into four subgroups based on the type of irrigant used. Group IA, IIA, 5.25% NaOCl; Group IB, IIB, 2% CHX; Group IC, IIC, QMix™ 2 in 1; and Group ID, IID, 0.9% saline (the control group). Ten microliters of the sample from each canal was taken and was placed on Brain Heart Infusion agar and Sabouraud dextrose agar. The plates were incubated at 37°C for 24 h and colony forming units (CFUs) that were grown were counted. Data was analyzed with analysis of variance (ANOVA) followed by post-hoc Games-Howell test. The greatest antimicrobial effects were observed in samples treated with QMix™ 2 in 1 (P < 0.001). No statistical significant difference was found between 5.25% NaOCl and 2% CHX (P > 0.001) against E. faecalis and C. albicans. QMix™ 2 in 1 demonstrated significant antimicrobial efficacy against E. faecalis and C. albicans.
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ISSN:0972-0707
0974-5203
DOI:10.4103/0972-0707.153067