Sample size calculation in medical studies

Optimum sample size is an essential component of any research. The main purpose of the sample size calculation is to determine the number of samples needed to detect significant changes in clinical parameters, treatment effects or associations after data gathering. It is not uncommon for studies to...

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Bibliographic Details
Published inGastroenterology and hepatology from bed to bench Vol. 6; no. 1; pp. 14 - 17
Main Authors Pourhoseingholi, Mohamad Amin, Vahedi, Mohsen, Rahimzadeh, Mitra
Format Journal Article
LanguageEnglish
Published Iran Research Institute for Gastroenterology and Liver Diseases 2013
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Special
Sample size
Medical studies
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Summary:Optimum sample size is an essential component of any research. The main purpose of the sample size calculation is to determine the number of samples needed to detect significant changes in clinical parameters, treatment effects or associations after data gathering. It is not uncommon for studies to be underpowered and thereby fail to detect the existing treatment effects due to inadequate sample size. In this paper, we explain briefly the basic principles of sample size calculations in medical studies.
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ISSN:2008-2258
2008-4234