2-(2-Hydroxy-ethyl-amino)-3-phenyl-1-benzofuro[3,2-d]pyrimidin-4(3H)-one dichloro-methane hemisolvate

• Published in: Acta crystallographica. Section E, Structure reports online Vol. 65; no. Pt 6; p. o1330
• Main Authors: Zhang, Zheng-Hong, Liu, Xiao-Ling, Chen, Long-Ju
• Format: Journal Article
• Language: English
• Published: United States International Union of Crystallography 20.05.2009
• Subjects: Organic Papers
• ISSN: 1600-5368; 1600-5368
• DOI: 10.1107/S1600536809017814

In the title compound, C(18)H(15)N(3)O(3)·0.5CH(2)Cl(2), the fused ring benzofuro[2,3-d]pyrimidine system is essentially planar [maximum deviation 0.029 (1) Å]. The planes of the pyrimidinone and phenyl rings are nearly perpendicular [dihedral angle = 87.50 (14)°]. The packing of the mol-ecules in the crystal structure is governed mainly by inter-molecular O-H⋯O and N-H⋯O hydrogen-bonding inter-actions and inter-molecular π-π inter-actions between benzofuro[3,2-d]pyrimidine units [the interplanar distances are ca 3.4 and 3.5 Å, and the distances between adjacent ring centroids are in the range 3.64 (1)-3.76 (1) Å]. The dichloromethane solvent molecule lies on a special position.