Antimicrobial efficacy assessment of multi-use solution to disinfect hydrophilic contact lens, in vitro

• Published in: Arquivos brasileiros de oftalmologia Vol. 72; no. 5; pp. 626 - 630
• Main Authors: Lui, Aline Cristina Fioravanti, Netto, Adamo Lui, Silva, Cely Barreto da, Hida, Richard, Mendes, Thais Sousa, Lui, Giovana Arlene Fioravanti, Gemperli, Daniela Barbosa, Vital, Enderson Dantas
• Format: Journal Article
• Language: English; Portuguese
• Published: Brazil Conselho Brasileiro de Oftalmologia 01.09.2009
• Subjects: Animals; Bacteria - drug effects; Bacteria - growth & development; Biguanides - pharmacology; Candida albicans - drug effects; Candida albicans - growth & development; Colony Count, Microbial; Contact Lens Solutions - pharmacology; Contact Lenses, Hydrophilic - microbiology; Disinfectants - pharmacology; Klebsiella - drug effects; Klebsiella - growth & development; OPHTHALMOLOGY; Polymers - pharmacology; Propylamines - pharmacology; Propylamines - standards; Pseudomonas aeruginosa - drug effects; Pseudomonas aeruginosa - growth & development; Staphylococcus aureus - drug effects; Staphylococcus aureus - growth & development; Staphylococcus epidermidis - drug effects; Staphylococcus epidermidis - growth & development; Candida albicans; Keratitis; Conjuntiva; Disinfection; Desinfecção; Ceratite; Lentes de contato hidrofílicas; Stapylococcus aureus; Staphylococcus epidermidis; Solutions; Contact lenses, hydrophilic; Pseudomonas aeruginosa; Conjuctiva; Klebsiella pneumoniae; Soluções
• ISSN: 1678-2925; 1678-2925
• DOI: 10.1590/S0004-27492009000500005

To evaluate the efficacy of disinfecting solutions in hydrophilic contact lenses (CL). Two multi-use solutions denominated solution A (0.001% polyquaternium-1 and 0.0005% myristamidopropyl dimethylamine) and solution B (0.0001% polyaminopropyl biguanide) were used. The solutions were tested in hydrophilic contact lenses infected with Pseudomonas aeruginosa (ATCC27583), Staphylococcus epidermidis (ATCC1226), Klebsiella pneumoniae (ATCC13883), Staphylococcus aureus (ATCC25923) and Candida albicans (ATCC 10231) and the decrease in microorganisms growth after the hydrophilic contact lenses were cleaned with the respective solutions was verified. The manufacture's instructions were followed. A decrease of 90% of Pseudomonas aeruginosa, Staphylococcus epidermidis, Staphylococcus aureus, Candida albicans and a decrease 100% of Klebsiella pneumoniae was observed. The solutions decreased the amount of microorganisms tested.