Pediatric rhabdomyosarcomas in Tunisia

Rhabdomyosarcoma is the most common soft tissue sarcoma in the first two decades of life. Since there is a paucity of reports on the pattern of its occurrence in Tunisia, we here analysed the epidemiological pattern, clinical features, and pathology. We retrospectively studied 30 consecutive cases o...

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Bibliographic Details
Published inAsian Pacific journal of cancer prevention : APJCP Vol. 11; no. 5; p. 1325
Main Authors Missaoui, Nabiha, Landolsi, Hanène, Jaidene, Lilia, Anjorin, Affissath, Abdelkader, Atef Ben, Yaacoubi, Mohamed Tahar, Hmissa, Sihem
Format Journal Article
LanguageEnglish
Published Thailand 2010
Subjects
Adolescent
Child
Child, Preschool
Head and Neck Neoplasms - therapy
Humans
Infant
Infant, Newborn
Registries
Retrospective Studies
Rhabdomyosarcoma - epidemiology
Rhabdomyosarcoma - pathology
Soft Tissue Neoplasms - epidemiology
Soft Tissue Neoplasms - pathology
Tunisia - epidemiology
Urologic Neoplasms - therapy
Tunisia
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Summary:Rhabdomyosarcoma is the most common soft tissue sarcoma in the first two decades of life. Since there is a paucity of reports on the pattern of its occurrence in Tunisia, we here analysed the epidemiological pattern, clinical features, and pathology. We retrospectively studied 30 consecutive cases of histologically proven rhabdomyosarcoma in children aged 0-15 years extracted from the database of the Cancer Registry of the Center of Tunisia for the period 1993-2007. Rhabdomyosarcomas represented 53.6% of soft tissue sarcomas and 3.8% of all children cancer cases registered during this period. The male/female ratio was 2.7 with a mean age at diagnosis of 5.9 years. The embryonal subtype was the most frequent (60%) and the two most common sites of disease were the head and neck (50%) and genito-urinary tract(23.3%). Chemotherapy was used in 90% of patients; 43.3% of patients had radical surgery and 26.7% of patients received radiation therapy. The epidemiology, pathology and clinical features of rhabdomyosarcoma in Tunisian children are close to those reported from other countries.
ISSN:2476-762X