Widespread vesiculobullous eruption in a 16-year-old male

Bullous systemic lupus erythematosus (BSLE) is a rare but distinct disease, characterized by vesiculobullous skin eruptions and systemic lupus erythematosus (SLE). It can arise either before or after a diagnosis of SLE has been established. BSLE is characterized by a dermatitis herpetiformis-like hi...

Full description

Saved in:
Bibliographic Details
Published inActa dermatovenerologica Alpina, Panonica, et Adriatica Vol. 19; no. 3; p. 19
Main Authors Pižem, J, Vizjak, A, Tomšič, M, Luzar, B
Format Journal Article
LanguageEnglish
Published Slovenia 01.10.2010
Subjects
Adolescent
Adrenal Cortex Hormones - administration & dosage
Diagnosis, Differential
Fluorescent Antibody Technique, Direct
Humans
Immunohistochemistry
Lupus Erythematosus, Cutaneous - complications
Lupus Erythematosus, Cutaneous - diagnosis
Lupus Erythematosus, Cutaneous - drug therapy
Male
Skin Diseases, Vesiculobullous - complications
Skin Diseases, Vesiculobullous - diagnosis
Skin Diseases, Vesiculobullous - drug therapy
Online AccessGet full text

Cover

More Information
Summary:Bullous systemic lupus erythematosus (BSLE) is a rare but distinct disease, characterized by vesiculobullous skin eruptions and systemic lupus erythematosus (SLE). It can arise either before or after a diagnosis of SLE has been established. BSLE is characterized by a dermatitis herpetiformis-like histology and an autoimmunity to type VII collagen. It must be differentiated from other autoimmune vesiculobullous diseases such as epidermolysis bullosa acquisita, dermatitis herpetiformis, linear IgA disease, and bullous pemphigoid. A combination of clinical, histological, and immunofluorescence findings are necessary to establish a diagnosis of BSLE. We present a case of BSLE to illustrate and emphasize the need for an integrative diagnostic approach.
ISSN:1581-2979