Cutaneous leishmaniasis of the vermilion border of the upper lip extending to the oral mucosa

Cutaneous leishmaniasis is endemic in Morocco. Mucosal involvement is rare. We report a case in Morocco of cutaneous leishmaniasis of the vermilion border of the upper lip extending to the oral mucosa due to Leishmania tropica. A 15-year-old girl was seen with 2 ulcerated lesions, present for 4 mont...

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Bibliographic Details
Published inAnnales de dermatologie et de vénéréologie Vol. 147; no. 2; p. 116
Main Authors Elfatoiki, F Z, Boumezzourh, A, Maksouri, H, Elkhalfaoui, N, Dessay, M, Riyad, M, Chiheb, S
Format Journal Article
LanguageEnglish
French
Published France 01.02.2020
Subjects
Lip
Fluconazole
Atteinte muqueuse
L. tropica
Leishmaniasis
Leishmaniose cutanée
Mucosal involvement
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Summary:Cutaneous leishmaniasis is endemic in Morocco. Mucosal involvement is rare. We report a case in Morocco of cutaneous leishmaniasis of the vermilion border of the upper lip extending to the oral mucosa due to Leishmania tropica. A 15-year-old girl was seen with 2 ulcerated lesions, present for 4 months, situated on the left cheek and vermilion border and extending to the oral mucosa. The diagnosis of leishmaniasis was confirmed by direct examination revealing high numbers of Leishmania amastigotes. Culture of the offending organism in NNN medium and isoenzymatic characterization resulted in identification of L. tropica. Treatment with meglumine antimoniate (Glucantime) was ineffective. The outcome was good after treatment with fluconazole. In Morocco, cutaneous leishmaniasis with mucosal involvement is rare, and usually develops as a complication of cutaneous leishmaniasis via direct extension.
ISSN:0151-9638
DOI:10.1016/j.annder.2019.09.600