Antibiotic prophylaxis in acute nonperforated appendicitis. The Danish Multicenter Study Group III

• Published in: Annals of surgery Vol. 209; no. 3; pp. 307 - 311
• Main Authors: Bauer, T, Vennits, B, Holm, B, Hahn-Pedersen, J, Lysen, D, Galatius, H, Kristensen, E S, Graversen, P, Wilhelmsen, F, Skjoldborg, H
• Format: Journal Article
• Language: English
• Published: United States 01.03.1989
• Subjects: Abdomen; Abscess - prevention & control; Acute Disease; Adult; Appendectomy; Appendicitis - surgery; Cefoxitin - therapeutic use; Denmark; Female; Humans; Male; Multicenter Studies as Topic; Premedication; Prospective Studies; Random Allocation; Surgical Wound Infection - prevention & control; Denmark

In a prospective, block-randomized, multicenter study, the safety and efficacy of cefoxitin in preoperative prophylaxis were studied. 1735 patients undergoing appendectomy were evaluable, and half of these patients received 2 g of cefoxitin before undergoing operation. The patients were divided into...