Adherence and cognitive performance in schizophrenia

It is known that many patients with schizophrenia show non-adherence with regard to antipsychotic medication. Furthermore, many studies indicate cognitive deficits in schizophrenic patients. In this review, we compare the results of studies examining the relationship of non-adherence and cognitive p...

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Bibliographic Details
Published inFortschritte der Neurologie-Psychiatrie Vol. 79; no. 2; p. 73
Main Authors Spiekermann, A, Schulz, M, Behrens, J, Driessen, M, Rahn, E, Beblo, T
Format Journal Article
LanguageGerman
Published Germany 01.02.2011
Subjects
Antipsychotic Agents - therapeutic use
Cognition - physiology
Humans
Interview, Psychological
Monitoring, Physiologic
Patient Compliance
Psychomotor Performance - physiology
Schizophrenia - drug therapy
Schizophrenic Psychology
Self Medication
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Summary:It is known that many patients with schizophrenia show non-adherence with regard to antipsychotic medication. Furthermore, many studies indicate cognitive deficits in schizophrenic patients. In this review, we compare the results of studies examining the relationship of non-adherence and cognitive performance. Based on a systematic literature review, the impact of cognitive performance on the adherence behaviour of patients with schizophrenia was examined. We found 18 studies analysing the impact of cognitive performance on adherence behaviour. Most studies indicated that patients with stronger cognitive impairments show lower adherence behaviour. Possible causal mechanisms are discussed.
ISSN:1439-3522
DOI:10.1055/s-0029-1245622