Analysis of the changes in the mass of the internal organs in a toxicological experiment

The authors describe a method for the evaluation of the changes in the mass of the animals' internal organs in a toxicological experiment. The method is based on the use of a regression analysis. The method permits evaluating the action of a factor on the mass of the organs, with the exception...

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Bibliographic Details
Published inFarmakologiia i toksikologiia Vol. 47; no. 5; p. 113
Main Authors Tikhonov, V N, Shitikov, V K, Miroshnichenko, I A, Kovalev, A F
Format Journal Article
LanguageRussian
Published Russia (Federation) 01.09.1984
Subjects
Animals
Body Weight - drug effects
Kidney - drug effects
Liver - drug effects
Organ Size - drug effects
Rats
Regression Analysis
Spleen - drug effects
Toxicology - methods
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Summary:The authors describe a method for the evaluation of the changes in the mass of the animals' internal organs in a toxicological experiment. The method is based on the use of a regression analysis. The method permits evaluating the action of a factor on the mass of the organs, with the exception of the effect of a change in the body mass in an experiment and initial weigh heterogeneity in animal groups.
ISSN:0014-8318