Application of generative design and additive manufacturing for scaffold fabrication

• Published in: AIP conference proceedings Vol. 2962; no. 1
• Main Authors: Ghassan, Mohammad, Garg, Utsav, Prakash, Jibin, Mufeed, C. P., Francis, Vishal
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Melville American Institute of Physics 30.01.2024
• Subjects: Additive manufacturing; Biocompatibility; Manufacturing; Pore size; Scaffolding; Scaffolds; Tissue engineering
• ISSN: 0094-243X; 1551-7616
• DOI: 10.1063/5.0194271

Scaffold design and fabrication plays an important role in tissue engineering. Conventional manufacturing processes for fabrication of scaffolds have limitations with respect to the controlled architecture and resolution required. The issue can be alleviated by using additive manufacturing (AM) technology. AM is a layer-by-layer fabrication technique which can fabricate complex structures with adequate resolutions. This characteristic of the process is suitable for scaffold fabrication. Moreover, the design aspect of the scaffolds such as pore size, density and structure also significantly influence the performance of the scaffold. Generative design is an AI based approach to design features with improved characteristics. Utilizing this approach to design scaffold is a subject of study which needs to be investigated. The present papers discuss about the various manufacturing techniques available for scaffold fabrication and compares them with the additive manufacturing techniques. Moreover, prospects of scaffold design using generative approach is also discussed along with the desired biocompatible properties required for scaffolding.