Toxoplasmic scleritis

Although toxoplasmosis is the most common infectious cause of posterior intraocular inflammation, it is rarely described in association with scleritis. The authors present five cases of toxoplasmosis with scleritis. Two of the five cases were diagnosed clinically and serologically as having toxoplas...

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Bibliographic Details
Published inOphthalmology (Rochester, Minn.) Vol. 95; no. 10; p. 1399
Main Authors Schuman, J S, Weinberg, R S, Ferry, A P, Guerry, R K
Format Journal Article
LanguageEnglish
Published United States 01.10.1988
Subjects
Adult
Aged
Aged, 80 and over
Animals
Antibodies, Protozoan - analysis
Chorioretinitis - diagnosis
Chorioretinitis - etiology
Chorioretinitis - pathology
Female
Humans
Male
Scleritis - diagnosis
Scleritis - etiology
Scleritis - pathology
Toxoplasma - isolation & purification
Toxoplasmosis, Ocular
Uveitis - etiology
Uveitis - immunology
Uveitis - pathology
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Summary:Although toxoplasmosis is the most common infectious cause of posterior intraocular inflammation, it is rarely described in association with scleritis. The authors present five cases of toxoplasmosis with scleritis. Two of the five cases were diagnosed clinically and serologically as having toxoplasmosis. Their retinochoroiditis and scleritis responded well to medical therapy. Retinochroiditis and scleritis that was refractory to treatment developed in the other three patients, two of whom had been receiving immunosuppressive therapy for systemic diseases. Their therapeutic regimens did not include treatment for toxoplasmosis. All three eyes became blind and were enucleated. Results of pathologic examination of all three enucleated eyes showed Toxoplasma gondii in the retina. There was severe inflammation of the retina, choroid, and sclera. Toxoplasmosis should be considered in the clinical differential diagnosis of scleritis associated with retinochoroiditis, particularly in immunosuppressed patients.
ISSN:0161-6420