Genetics of Borrelia burgdorferi

Structural analysis by electronmicroscopy and pulsed field agarose gel electrophoresis of the genome of Borrelia burgdorferi has revealed a 1000 kilobase (kb) chromosome and a unique type of extra chromosomal linear DNA, as well as supercoiled circular DNA. The plasmid DNA ranged in size from 1.5 to...

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Bibliographic Details
Published inScandinavian journal of infectious diseases. Supplementum Vol. 77; p. 102
Main Authors Bergström, S, Barbour, A G, Garon, C F, Hindersson, P, Saint Girons, I, Schwan, T G
Format Journal Article
LanguageEnglish
Published England 1991
Subjects
Animals
Antigens, Bacterial - genetics
Bacterial Outer Membrane Proteins - genetics
Borrelia burgdorferi Group - genetics
Chromosomes, Bacterial - chemistry
Chromosomes, Bacterial - ultrastructure
DNA, Bacterial - chemistry
DNA, Bacterial - ultrastructure
Humans
Operon
Plasmids
Polymorphism, Genetic
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Summary:Structural analysis by electronmicroscopy and pulsed field agarose gel electrophoresis of the genome of Borrelia burgdorferi has revealed a 1000 kilobase (kb) chromosome and a unique type of extra chromosomal linear DNA, as well as supercoiled circular DNA. The plasmid DNA ranged in size from 1.5 to 50 kb. Gene mapping of the ospA and ospB genes have placed them on the 49 kb linear plasmid molecule. The osp operon of B. burgdorferi has been extensively characterized at the molecular level.
ISSN:0300-8878