Prevention of gallstone recurrence by non-steroidal anti-inflammatory drugs
In laboratory animals, non-steroidal anti-inflammatory drugs (NSAIDs) are reported to inhibit diet-induced gallstone formation. To see if these drugs had a similar effect in man, 82 patients who had taken part in a comparison of ursodeoxycholic acid, placebo, and diet for prevention of gallstone rec...
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Published in | The Lancet (British edition) Vol. 2; no. 8622; p. 1223 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
England
26.11.1988
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Subjects | |
Online Access | Get more information |
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Summary: | In laboratory animals, non-steroidal anti-inflammatory drugs (NSAIDs) are reported to inhibit diet-induced gallstone formation. To see if these drugs had a similar effect in man, 82 patients who had taken part in a comparison of ursodeoxycholic acid, placebo, and diet for prevention of gallstone recurrence were sent questionnaires about their use of NSAIDs during the period of the trial. 75 replied. After a mean follow-up of 33 (SEM 4) months none of the 12 regular users of NSAIDs had had gallstone recurrences, compared with 20 of the 63 who never or rarely used these drugs (p less than 0.02). |
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ISSN: | 0140-6736 |