Hemolytic uremic syndrome associated with cisplatin therapy

An adolescent with a small round cell tumor of the chest wall, who was treated with cisplatin, developed hemolytic uremic syndrome with severe hypertension, which ultimately contributed to her death. Cisplatin's role as a possible causative agent of this syndrome is discussed. Recommendations a...

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Bibliographic Details
Published inThe American journal of pediatric hematology/oncology Vol. 9; no. 4; p. 295
Main Authors Weinblatt, M E, Kahn, E, Scimeca, P G, Kochen, J A
Format Journal Article
LanguageEnglish
Published United States 1987
Subjects
Adolescent
Cisplatin - adverse effects
Female
Hemolytic-Uremic Syndrome - chemically induced
Hemolytic-Uremic Syndrome - pathology
Humans
Kidney - pathology
Sarcoma - drug therapy
Thoracic Neoplasms - drug therapy
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Summary:An adolescent with a small round cell tumor of the chest wall, who was treated with cisplatin, developed hemolytic uremic syndrome with severe hypertension, which ultimately contributed to her death. Cisplatin's role as a possible causative agent of this syndrome is discussed. Recommendations are made for monitoring abnormalities that may signal the onset of this potential complication.
ISSN:0192-8562