The discovery of LY293111, a novel, potent and orally active leukotriene B4 receptor antagonist of the biphenylphenol class

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Bibliographic Details
Published inAdvances in experimental medicine and biology Vol. 400A; p. 381
Main Authors Sofia, M J, Floreancig, P, Bach, N, Baker, S R, Nelson, K, Sawyer, J S, Baldwin, R, Cockerham, S L, Fleisch, J H, Froelich, L L, Jackson, W T, Marder, P, Roman, C R, Saussy, Jr, D L, Silbaugh, S A, Spaethe, S M, Stengel, P W
Format Journal Article
LanguageEnglish
Published United States 1997
Subjects
Administration, Oral
Animals
Benzoates - administration & dosage
Benzoates - pharmacology
Bronchoconstriction - drug effects
Cell Membrane - metabolism
Guinea Pigs
Humans
Leukotriene B4 - pharmacology
Lung - physiology
Neutrophils - drug effects
Neutrophils - physiology
Phenols - pharmacology
Receptors, Leukotriene B4 - antagonists & inhibitors
Receptors, Leukotriene B4 - metabolism
Structure-Activity Relationship
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ISSN:0065-2598
DOI:10.1007/978-1-4615-5325-0_51