A case report on the effect of micrografting in the healing of chronic and complex burn wounds

• Published in: International journal of burns and trauma Vol. 10; no. 1; pp. 15 - 20
• Main Authors: Andreone, Alessandro, de Hollander, Daan
• Format: Journal Article
• Language: English
• Published: United States e-Century Publishing Corporation 01.01.2020
• Subjects: Case Report; non-healing wounds; Micrografts; chronic; autologous; burns
• ISSN: 2160-2026; 2160-2026

Different approaches can be used to repair extensive burn injury and chronic wounds, including full and split thickness skin grafts, temporising matrices and scaffolds, and composite cultured skin products. The use of non-cultured or autologous skin cells suspension in chronic burn is well established, but despite this no significant literature has been realized. The Rigenera micrografting technology is an innovative technique allowing to obtain a suspension of autologous micrografts that can be applied over the wounds in a combined methodology specifically developed and based on the both injections of the wound edges and spraying over the wound bed of this suspension. A black male patient with open wounds on the back already treated with a traditional split skin graft, present a 10% of wounds not healing. Then, the patient was treated with micrografts suspension obtained by mechanical disaggregation of small split skin biopsies using the Rigeneracons medical device. Micrografts were directly injected and sprayed in the wounds. The combination of injection and sprayed micrografts solution over the wounds achieved full closure over 10% over a period of 6 months. The follow up more than 2 years showed stable wounds with no breakdown in the epidermis. The final cosmetic and functional results obtained with micrografting on chronic burn wounds is a valid alternative when all the other options cannot provide wound closure.