Analysis of neutralized antibody level of the poliomyelitis in healthy population in Fujian province

• Published in: Zhonghua shi yan he lin chuang bing du xue za ji Vol. 24; no. 5; p. 352
• Main Authors: He, Ai-hua, Wang, Hong, Yang, Xiu-hui, Xu, Jiang-yang, Zhang, Hong-rong, Huang, Li-fang
• Format: Journal Article
• Language: Chinese
• Published: China 01.10.2010
• Subjects: Adolescent; Adult; Antibodies, Neutralizing - blood; Antibodies, Neutralizing - immunology; Antibodies, Viral - blood; Antibodies, Viral - immunology; Child; Child, Preschool; China; Female; Health Status; Humans; Infant; Male; Middle Aged; Poliomyelitis - immunology; Poliomyelitis - prevention & control; Poliomyelitis - virology; Poliovirus Vaccine, Oral - administration & dosage; Poliovirus Vaccine, Oral - immunology; Population Surveillance; Vaccination; Young Adult; China
• ISSN: 1003-9279
• DOI: 10.3760/cma.j.issn.1003-9279.2010.05.011

To understand the neutralized antibody level of the poliomyelitis among healthy people and provide scientific evidence for the immunization strategy since routine and intensified immunization with oral polio vaccine (OPV) in Fujian province. The poliomyelitis antibody level of healthy people were detected by neutralization test of the micro cells. The neutralizing antibody positive rates were 99.0%, 99.3%, 97.5% and GMTs were 1:79.1, 1:31.2, 1:24.7 for polio I, II, III respectively in 400 serum specimens from 1-59 years old. GMTs present a trend of decreasing as age's increasing. A protective barrier had been built against poliomyelitis in healthy people in Fujian province through routine and intensified immunization with OPV.