Escherichia coli defects caused by null mutations in dnaK and dnaJ genes

• Published in: Acta microbiologica Polonica Vol. 46; no. 1; p. 7
• Main Authors: Paciorek, J, Kardyś, K, Lobacz, B, Wolska, K I
• Format: Journal Article
• Language: English
• Published: Poland 1997
• Subjects: Bacterial Proteins - biosynthesis; Bacterial Proteins - genetics; Bacterial Proteins - physiology; DNA, Bacterial - biosynthesis; Escherichia coli - genetics; Escherichia coli - growth & development; Escherichia coli - metabolism; Escherichia coli Proteins; Genes, Bacterial - physiology; Heat-Shock Proteins - genetics; Heat-Shock Proteins - physiology; HSP40 Heat-Shock Proteins; HSP70 Heat-Shock Proteins - genetics; HSP70 Heat-Shock Proteins - physiology; Mutation; Temperature

Escherichia coli dnaJ and dnaKdnaJ mutants are defective in cell growth and survival at high temperature. Lack of DnaK and DnaJ proteins results in cell filamentation and leads to the defect in motility. Synthesis of DNA and protein is inhibited at 42 degrees C, especially in double-deletion mutant....