Effects of low-intensity pulsed ultrasound in repairing injured articular cartilage

To investigate the effects of low-intensity pulsed ultrasound in repairing injured articular cartilage. Ten adult New Zealand rabbits with bilateral full-thickness osteochondral defects on the cartilage surface of intercondylar fossas were used in this study. The wounds in the left knees were treate...

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Bibliographic Details
Published inChinese journal of traumatology Vol. 8; no. 3; p. 175
Main Authors Jia, Xiao-lin, Chen, Wen-zhi, Zhou, Kun, Wang, Zhi-biao
Format Journal Article
LanguageEnglish
Published China 01.06.2005
Subjects
Animals
Biopsy, Needle
Cartilage, Articular - injuries
Cartilage, Articular - pathology
Disease Models, Animal
Female
Immunohistochemistry
Knee Injuries - pathology
Knee Injuries - therapy
Male
Rabbits
Sensitivity and Specificity
Ultrasonic Therapy - methods
Wound Healing - physiology
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Summary:To investigate the effects of low-intensity pulsed ultrasound in repairing injured articular cartilage. Ten adult New Zealand rabbits with bilateral full-thickness osteochondral defects on the cartilage surface of intercondylar fossas were used in this study. The wounds in the left knees were treated with low-intensity pulsed ultrasound as the experimental group. The right knees received no treatment as the control group. All the animals were killed at 8 weeks after injury and the tissues in the wounds were collected for gross appearance grading, histological grading and proteoglycan quantity. The scores of the gross appearance grades, histological grades and the optical density of toluidine blue of the tissues in the experimental group were significantly higher than those of the controls at 8 weeks after injury (P < 0.05). Low-intensity pulsed ultrasound can accelerate the repair of injured articular cartilage.
ISSN:1008-1275