Physiological reactions of primates to 9-D immersion and head-down tilt

Purpose of the investigation was to compare physiological reactions of primates (Macaca mulatta) to microgravity simulated by immersion and head-down tilt (HDT). In immersion experiments, primates in waterproof suits were put into motion-restraining chairs and immersed into water (t=35.4 degrees C)...

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Bibliographic Details
Published inJournal of gravitational physiology Vol. 11; no. 2; p. P29
Main Authors Korolkov, V I, Krokotov, V P, Gordeev, Yu V, Lazarev, A O, Lobachik, V, Burkovskaya, T E, Dotsenko, M A, Durnova, G N, Kaplansky, A S, Chistiakov, I N, Vasilieva, O N
Format Journal Article
LanguageEnglish
Published United States 01.07.2004
Subjects
Adaptation, Physiological - physiology
Animals
Behavior, Animal
Body Fluids - physiology
Bone Diseases, Metabolic - etiology
Bone Diseases, Metabolic - physiopathology
Central Nervous System - physiology
Conditioning (Psychology)
Erythropoiesis - physiology
Head-Down Tilt
Hypokinesia - physiopathology
Immersion - physiopathology
Leg
Macaca mulatta
Muscular Atrophy - etiology
Muscular Atrophy - physiopathology
Plasma Volume - physiology
Restraint, Physical
Stress, Physiological
Weightlessness Simulation
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Summary:Purpose of the investigation was to compare physiological reactions of primates (Macaca mulatta) to microgravity simulated by immersion and head-down tilt (HDT). In immersion experiments, primates in waterproof suits were put into motion-restraining chairs and immersed into water (t=35.4 degrees C) breast-deep for 9 days. In 9-d HDT experiments, prone primates were motor restrained in dedicated tilt beds at -5 degrees. It was found that the CNS functioning was significantly affected, the plasma volume reduced and the marrow erythropoietic function declined. Atrophy developed in leg muscles on a backdrop of iliopectineal spongy osteopenia. Loss in hydration, inhibition of erythropoietic hemopoiesis and iliopectineal spongy osteopenia were more pronounced following immersion than HDT.
ISSN:1077-9248