Cytological grading of breast neoplasia and its correlation with histological grading

Cytological grading of breast cancer is not well established despite histological grading having gained a strong foothold. In our study we have analyzed 50 cases of breast carcinoma which included invasive ductal carcinoma, invasive lobular carcinoma, mucinous carcinoma, stromal sarcoma, apocrine ca...

Full description

Saved in:
Bibliographic Details
Published inIndian journal of pathology & microbiology Vol. 49; no. 2; pp. 208 - 213
Main Authors Ohri, Anupam, Jetly, Dhaval, Shukla, Kaushambi, Bansal, Rimpi
Format Journal Article
LanguageEnglish
Published India 01.04.2006
Subjects
Adult
Breast Neoplasms - pathology
Cytodiagnosis
Female
Histological Techniques
Humans
Middle Aged
Retrospective Studies
Online AccessGet full text

Cover

More Information
Summary:Cytological grading of breast cancer is not well established despite histological grading having gained a strong foothold. In our study we have analyzed 50 cases of breast carcinoma which included invasive ductal carcinoma, invasive lobular carcinoma, mucinous carcinoma, stromal sarcoma, apocrine carcinoma, papillary carcinoma. Papanicolaou smears were graded according to established Hunt's, Simplified Black and Modified Black grading systems. They were then compared with the Scarff Bloom Richardson grading system. Simplified Black grading system has been recommended for cytological grading of breast neoplasia because of its lucidity and its reproducibility. Cytological grading of breast neoplasia is important for neo adjuvant chemotherapy and also for predicting the prognosis of the patient on FNAC alone. Incorporation of other parameters like apoptosis and bcl-2 is also recommended.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0377-4929