A study of side-effects of Pandemrix® influenza (H1N1) vaccine on board a Norwegian naval vessel

The frigate His Norwegian Majesty's ship (HNoMS) Fridtjof Nansen was participating in operations in the Gulf of Aden in support of the EU mission tasked with protecting vessels from the threat of piracy. The crew was therefore prioritized and given the first batch of Influenza A (H1N1) vaccine...

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Published inInternational maritime health Vol. 62; no. 4; pp. 246 - 250
Main Authors Munch, Johan Storm, Johnsen, Bjørn Helge, Birkeland, Ingelin, Finne, Morten, Utkilen, Torun, Bøe, Tommy, Mjølhus, Gry, Sommerfelt-Pettersen, Jan
Format Journal Article
LanguageEnglish
Published Poland Wydawnictwo Via Medica 2010
Subjects
Arthralgia - etiology
Fatigue - etiology
Fever - etiology
Headache - etiology
Humans
Immunization
Influenza
Influenza A Virus, H1N1 Subtype
Influenza Vaccines - adverse effects
Influenza Vaccines - therapeutic use
Influenza, Human - prevention & control
Military Personnel
Naval Medicine
Norway
Sick Leave
Sleep Wake Disorders - etiology
Surveys and Questionnaires
Vaccination
Vaccines
Norway
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Summary:The frigate His Norwegian Majesty's ship (HNoMS) Fridtjof Nansen was participating in operations in the Gulf of Aden in support of the EU mission tasked with protecting vessels from the threat of piracy. The crew was therefore prioritized and given the first batch of Influenza A (H1N1) vaccine (Pandemrix(®)). To investigate the type, frequency, and intensity of side effects after whole-crew vaccination with Pandemrix vaccine in healthy subjects in a controlled environment. A hundred and thirty-three members of the crew were vaccinated, and then they participated in the study. The side effects of the vaccination were evaluated through a survey. Seventy-five per cent of the vaccinated sailors reported adverse reactions to the vaccine, with 9% not being able to perform their daily duties for one day. Muscle pain, headaches, malaise, and fatigue were the most frequent symptoms reported. The vaccination program using Pandemrix H1N1 vaccine resulted in a high rate of side effects, which were generally mild and resolved within a few days. No serious lasting side effects of the vaccination were reported or registered. The adverse effects of the vaccination did not affect the operational capacity of the vessel.
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ISSN:1641-9251
2081-3252