Determination of benzene in urine by static headspace gas chromatography

This paper describes the application of static headspace gas chromatography in determining benzene in urine. The method was analytically validated for sensitivity (DL = 42 ng/l), repeatability (RSD = 3% and 4%), and accuracy (71%), and was applied in measuring urine benzene in nonsmokers (N = 14) an...

Full description

Saved in:
Bibliographic Details
Published inArhiv za higijenu rada i toksikologiju Vol. 53; no. 3; pp. 197 - 202
Main Authors Skender, Ljiljana, Brcić, Irena, Zuzul, Silva
Format Journal Article
LanguageEnglish
Published Croatia 01.09.2002
Subjects
Adult
Benzene - analysis
Chromatography, Gas - methods
Environmental Pollutants - urine
Humans
Sensitivity and Specificity
Smoking - urine
Urinalysis - methods
Online AccessGet full text

Cover

More Information
Summary:This paper describes the application of static headspace gas chromatography in determining benzene in urine. The method was analytically validated for sensitivity (DL = 42 ng/l), repeatability (RSD = 3% and 4%), and accuracy (71%), and was applied in measuring urine benzene in nonsmokers (N = 14) and smokers (N = 18). All urine samples had measurable benzene concentrations. The method proved sensitive enough to establish a significant statistical difference (P < 0.000614) in urine benzene concentrations between smokers (mean = 760; range = 181-1869 ng/l) and nonsmokers (mean = 214; range = 61-515 ng/l).
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0004-1254