Effect of verapamil on chemiluminescence of peripheral blood neutrophils during hemodialysis in chronic uremic patients
Luminol-dependent chemiluminescence of resting and opsonized zymosan-activated neutrophils isolated from the peripheral blood was determined in 10 chronic uremic patients during early period of hemodialysis without verapamil or preceded by verapamil injection. Verapamil was found to diminish depress...
Saved in:
Published in | Archivum Immunologiae et Therapiae Experimentalis Vol. 37; no. 1-2; p. 149 |
---|---|
Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Switzerland
1989
|
Subjects | |
Online Access | Get more information |
Cover
Loading…
Summary: | Luminol-dependent chemiluminescence of resting and opsonized zymosan-activated neutrophils isolated from the peripheral blood was determined in 10 chronic uremic patients during early period of hemodialysis without verapamil or preceded by verapamil injection. Verapamil was found to diminish depression of neutrophil chemiluminescence both at rest and following activation with opsonized zymosan. The drug also diminished transient hemodialysis neutropenia. The results seem to indicate that verapamil may exert beneficial effects on inflammatory reactions induced by hemodialysis in chronic uremics. |
---|---|
ISSN: | 0004-069X |