An outbreak of Eltor cholera in Aizwal town of Mizoram, India

During the months of May, June and through early part of July 1994, an unusual occurrence of severe dehydrating watery diarrhoea cases and deaths were reported from Aizwal town, the capital of Mizoram, a North-Eastern state of India. Vibrio cholerae 01 biotype Eltor, the causative agent responsible...

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Bibliographic Details
Published inJournal of communicable diseases Vol. 32; no. 3; p. 207
Main Authors Sengupta, P G, Niyogi, S K, Bhattacharya, S K
Format Journal Article
LanguageEnglish
Published India 01.09.2000
Subjects
Adolescent
Adult
Anti-Bacterial Agents - pharmacology
Child
Child, Preschool
Cholera - epidemiology
Cholera - microbiology
Cholera - mortality
Diarrhea - epidemiology
Diarrhea - microbiology
Disease Outbreaks
Drug Resistance, Microbial
Drug Resistance, Multiple
Furazolidone - pharmacology
Hospitalization
Humans
India - epidemiology
Infant
Middle Aged
Monoamine Oxidase Inhibitors - pharmacology
Trimethoprim, Sulfamethoxazole Drug Combination - pharmacology
Vibrio cholerae - drug effects
Vibrio cholerae - isolation & purification
India
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Summary:During the months of May, June and through early part of July 1994, an unusual occurrence of severe dehydrating watery diarrhoea cases and deaths were reported from Aizwal town, the capital of Mizoram, a North-Eastern state of India. Vibrio cholerae 01 biotype Eltor, the causative agent responsible for this outbreak, was isolated from 50.0% of hospitalised cases. The disease affected older children and adults more (52.9%) than younger children below five years of age. Vibrio cholerae 01 strains isolated were uniformly resistant to furazolidone and co-trimoxazole, which are commonly advocated in the treatment of cholera specially in children of developing countries. Emergence of such resistant strain is alarming and is of great public health importance.
ISSN:0019-5138