Prothrombin time in first week of life with special reference to vitamin K administration

Prothrombin time was estimated in 100 neonates (80 full term and 20 preterm). Among the full term infants 50 were healthy and 30 sick. Prothrombin time was altered in neonates with birth hypoxia and prematurity (p less than 0.001). Vitamin K administration to anoxic babies resulted in improvement in...

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Published inIndian pediatrics Vol. 27; no. 7; pp. 723 - 725
Main Authors MATHUR, G. P, MATHUR, S, REETA GOENKA, BHALLA, J. N, AGARWAL, A, TRIPATHI, V. N
Format Journal Article
LanguageEnglish
Published New Delhi Indian Pediatrics 01.07.1990
Subjects
Biological and medical sciences
Blood. Blood coagulation. Reticuloendothelial system
Humans
Infant, Newborn - blood
Infant, Premature - blood
Medical sciences
Pharmacology. Drug treatments
Prothrombin Time
Tropical medicine
Vitamin K - administration & dosage
Vitamin K Deficiency Bleeding - prevention & control
Human
Premature
Chemotherapy
Neonatal
Newborn
Treatment
Prothrombin time
Asia
Hemorrhage
Nutritional deficiency
India
Vitamin K
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Summary:Prothrombin time was estimated in 100 neonates (80 full term and 20 preterm). Among the full term infants 50 were healthy and 30 sick. Prothrombin time was altered in neonates with birth hypoxia and prematurity (p less than 0.001). Vitamin K administration to anoxic babies resulted in improvement in prothrombin time after 48-72 hours (p less than 0.001). Four newborns has bleeding, 2 had anoxia and 2 were only in preterms who did not receive vitamin K after birth. It is concluded that vitamin K should be given to all preterms and those with difficult deliveries; term, healthy newborns do not need it.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0019-6061
0974-7559