Ketorolac tromethamine for postoperative analgesia in oral surgery

Sixty patients were randomly allocated to receive placebo or i.v. ketorolac tromethamine 30 mg during the induction of anaesthesia for dental removal. Pain score (VAS), mouth opening and oedema were evaluated. Pain intensity was assessed by the patient using a visual analog scale 1, 2, 6 and 24 hrs...

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Bibliographic Details
Published inActa anaesthesiologica belgica Vol. 46; no. 1; p. 25
Main Authors Pendeville, P E, Van Boven, M J, Contreras, V, Scholtes, J L, Fosseur, G, Lechien, P, Reychler, H
Format Journal Article
LanguageEnglish
Published Belgium 1995
Subjects
Adolescent
Adult
Analgesics - administration & dosage
Anti-Inflammatory Agents, Non-Steroidal - administration & dosage
Double-Blind Method
Drug Combinations
Edema - drug therapy
Female
Humans
Ketorolac Tromethamine
Male
Pain Measurement
Pain, Postoperative - diagnosis
Pain, Postoperative - drug therapy
Tolmetin - administration & dosage
Tolmetin - analogs & derivatives
Tooth Extraction
Tromethamine - administration & dosage
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Summary:Sixty patients were randomly allocated to receive placebo or i.v. ketorolac tromethamine 30 mg during the induction of anaesthesia for dental removal. Pain score (VAS), mouth opening and oedema were evaluated. Pain intensity was assessed by the patient using a visual analog scale 1, 2, 6 and 24 hrs after surgery. Mouth opening and oedema were evaluated at the same times by an observer not implicated in the study. In ketorolac group, pain relief was better at each considered time (VAS: p < 0.001). Oedema was also significantly lesser. There was no difference in mouth opening. No side effect was observed. These data suggest that ketorolac reduces post-oral surgery pain and oedema.
ISSN:0001-5164