Carcinomas of the pituitary: definition and review of the literature

Pituitary carcinomas are defined by their disconnected mode of extension, i.e. by the existence of intra- or extra-cerebral metastases. Since an invasive growth in the sella and its neighboring regions can also be noted in many pituitary adenomas, this invasion cannot be counted as a criterion for m...

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Bibliographic Details
Published inGeneral & diagnostic pathology Vol. 141; no. 2; p. 81
Main Authors Lübke, D, Saeger, W
Format Journal Article
LanguageEnglish
Published Germany 01.10.1995
Subjects
Adenoma - classification
Adenoma - pathology
Adrenocorticotropic Hormone - biosynthesis
Adult
Aged
Carcinoma - classification
Carcinoma - pathology
Carcinoma - secondary
Child
Cushing Syndrome - pathology
Humans
Middle Aged
Nelson Syndrome - pathology
Neoplasm Invasiveness
Neoplasm Metastasis - pathology
Pituitary Neoplasms - classification
Pituitary Neoplasms - metabolism
Pituitary Neoplasms - pathology
Prolactin - biosynthesis
Prolactinoma - pathology
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Summary:Pituitary carcinomas are defined by their disconnected mode of extension, i.e. by the existence of intra- or extra-cerebral metastases. Since an invasive growth in the sella and its neighboring regions can also be noted in many pituitary adenomas, this invasion cannot be counted as a criterion for malignancy. Almost all pituitary carcinomas stem from previously operated or irradiated invasive adenomas. Like adenomas, they are classified with regard to the presumable cell of origin and the hormone which was produced contingently. Together with 67 pituitary carcinomas already published, three own cases are subject to a critical, summarizing judgement.
ISSN:0947-823X