Cutaneous gangrene secondary to metastatic calcification in end stage renal failure : A case report

Metastatic calcification is a frequent association of chronic renal failure but skin involvement is accepted as a rare, albeit well recognised, complication accompanying the secondary hyperparathyroidism that results from renal impairment, although the aetiology remains unknown. Skin involvement can...

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Bibliographic Details
Published inSingapore medical journal Vol. 37; no. 4; pp. 438 - 440
Main Authors TAN, H. H, CHEONG, W. K
Format Journal Article
LanguageEnglish
Published Singapore Singapore Medical Association 01.08.1996
Subjects
Adult
Biological and medical sciences
Calcinosis - complications
Calcinosis - diagnosis
Fatal Outcome
Gangrene - complications
Gangrene - diagnosis
Humans
Hyperparathyroidism, Secondary - complications
Hyperparathyroidism, Secondary - diagnosis
Hyperparathyroidism, Secondary - surgery
Kidney Failure, Chronic - complications
Kidney Failure, Chronic - diagnosis
Kidney Transplantation
Male
Medical sciences
Nephrology. Urinary tract diseases
Nephropathies. Renovascular diseases. Renal failure
Renal failure
Skin Diseases - complications
Skin Diseases - pathology
Tropical medicine
Asia
Malaysia
Endocrinopathy
Kidney disease
Human
Skin disease
Secondary
Urinary system disease
Male
Terminal stage
Metastasis
Case study
Association
Parathyroid diseases
Renal failure
Calcification
Gangrene
Chinese
Complication
Skin
Hyperparathyroidism
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ISSN0037-5675

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Summary:Metastatic calcification is a frequent association of chronic renal failure but skin involvement is accepted as a rare, albeit well recognised, complication accompanying the secondary hyperparathyroidism that results from renal impairment, although the aetiology remains unknown. Skin involvement can take the form of metastatic calcinosis cutis or cutaneous gangrene resulting from vascular calcification. There have been reported cases which describe the healing of gangrenous areas following parathyroidectomy as well as use of dietary restriction of phosphorus and phosphate binding antacids(1-6). We report a case of a 35-year-old man with end stage renal failure who presented with cutaneous gangrene but who eventually succumbed despite a subtotal parathyroidectomy and review some of the literature concerning this subject.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Review-5
ObjectType-Feature-4
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ObjectType-Report-1
ObjectType-Article-3
ISSN:0037-5675