Remission of HIV-associated myelopathy after highly active antiretroviral therapy

HIV-associated myelopathy is the leading cause of spinal cord disease in HIV-infected patients. Typically, it affects individuals with low CD4 T cell counts, presenting with slowly progressive spastic paraparesis associated with dorsal column sensory loss as well as urinary disturbances. Other aetio...

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Published inJournal of postgraduate medicine (Bombay) Vol. 50; no. 3; pp. 195 - 196
Main Authors Fernández-Fernández, F J, de la Fuente-Aguado, J, Ocampo-Hermida, A, Iglesias-Castañón, A
Format Journal Article
LanguageEnglish
Published India Medknow Publications & Media Pvt. Ltd 01.07.2004
Subjects
Adult
Anti-HIV Agents - therapeutic use
Antiretroviral Therapy, Highly Active
Female
HIV Infections - complications
HIV Infections - drug therapy
HIV Protease Inhibitors - therapeutic use
Humans
Lamivudine - therapeutic use
Remission, Spontaneous
Ritonavir - therapeutic use
Spinal Cord Diseases - virology
Zidovudine - therapeutic use
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Summary:HIV-associated myelopathy is the leading cause of spinal cord disease in HIV-infected patients. Typically, it affects individuals with low CD4 T cell counts, presenting with slowly progressive spastic paraparesis associated with dorsal column sensory loss as well as urinary disturbances. Other aetiologies must be first ruled out before establishing the diagnosis. We report here the case of a 37-year-old woman with advanced HIV disease, who developed HIV-associated myelopathy. The patient showed a gradual improvement after beginning with highly active antiretroviral therapy and, finally, she achieved a complete functional recovery. In addition, neuroimaging and neurophysiological tests normalized.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
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ISSN:0022-3859
0972-2823