Versatile Ligands for Palladium‐Catalyzed Asymmetric Allylic Alkylation

Palladium complexes of the chiral diphosphanes 1 and 2 which possess a rigid backbone and a large bite angle catalyze the alkylation of allyl compounds with both high enantioselectivities and reaction rates, particularly with less sterically demanding substrates. 1: R=Me, X=S; 2: R=H, X=C(CH3)2.

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Bibliographic Details
Published inAngewandte Chemie International Edition Vol. 37; no. 22; pp. 3116 - 3118
Main Authors Dierkes, Peter, Ramdeehul, Shailesh, Barloy, Laurent, De Cian, Andre, Fischer, Jean, Kamer, Paul C. J., van Leeuwen, Piet W. N. M, Osborn, John A.
Format Journal Article
LanguageEnglish
Published Weinheim WILEY‐VCH Verlag GmbH 04.12.1998
Subjects
Alkylations
Asymmetric catalysis
Chiral ligands
Homogeneous catalysis
Palladium
Alkylations
Palladium
Chiral ligands
Asymmetric catalysis
Homogeneous catalysis
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Summary:Palladium complexes of the chiral diphosphanes 1 and 2 which possess a rigid backbone and a large bite angle catalyze the alkylation of allyl compounds with both high enantioselectivities and reaction rates, particularly with less sterically demanding substrates. 1: R=Me, X=S; 2: R=H, X=C(CH3)2.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:1433-7851
1521-3773
DOI:10.1002/(SICI)1521-3773(19981204)37:22<3116::AID-ANIE3116>3.0.CO;2-S